Description: L-Mimosine (also known as Leucenol; NSC69188) is a non-protein amino acid which acts as an iron chelator.
NSC348884 is a novel and potent nucleophosmin inhibitor that is able to disrupt oligomer formation and induces apoptosis, it inhibits cell proliferation at an IC50 of 1.7-4.0 μM in distinct cancer cell lines.
Mycophenolic acid (Mycophenolate) is an approved immunosuppressant drug used for preventing rejection in organ transplantation.
Kinetin Riboside, an analotg of cytokinin, is a potent activator of the Parkinson’s Disease-associated PTEN-induced Putative Kinase 1 (PINK1), and acts independently from mitochondrial depolarization.
Rhapontin is natural product.
PTC-028 is a potent and orally bioavailable compound that decreases BMI-1 levels by posttranslational modification.
ZZW-115 (ZZW115) is a novel and potent NUPR1 inhibitor (Kd=2.1 uM) with antitumor activity. It is the most active one in the family of TFP-derived compounds. NUPR1 is an intrinsically disordered protein (IDP) with an entirely disordered conformation
Bufotalin is a novel and potent anti-osteoblastoma agent.
Gemcitabine monophosphate disodium (GemMP) is a monophosphate analog of Gemcitabine (formerly also known as LY-188011, NSC 613327; dFdC; dFdCyd; gemcitabine; trade name: Gemzar), an antimetabolite anticancer drug, which is a potent DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.
Isoliensinine is a novel and potent bisbenzylisoquinoline alkaloid