Vortioxetine lactate (formerly Lu-AA21004 lactate; Trintellix; Brintellix) is the lactate salt of Vortioxetine, which is an atypical antidepressant which was approved in 2013 by the FDA for the treatment of major depressive disorder (MDD) in adults.
Almotriptan Malate (formerly LAS31416; LAS-31416; Almogran; Amignul; Almotrex; Axert), the maleate salt of Almotriptan which is an approved anti-migraine drug, is a potent and selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist.
Risperidone (R-64766; R64766 and Risperdal), an marketed atypical antipsychotic, is a potent multi-targeted antagonist for dopamine, serotonin, adrenergic and histamine receptors, it has been approved for use in the treatment of schizophrenia and bipolar disorder.
Duloxetine ((S)-Duloxetine; LY248686; LY-248686) is a serotonin-norepinephrine reuptake inhibitor (SNRI, Ki = 4.6 nM) used for treatment of major depressive disorder and generalized anxiety disorder (GAD), fibromyalgia and neuropathic pain.
Eptapirone (formerly known as F11440; L0068) is a potent, selective, high efficacy 5-HT1A receptor agonist with marked anxiolytic and antidepressant potential.
Buspirone HCl (MJ90221, MJ-90221, Buspar, MJ-9022-1, MJ9022 1, MJ9022-1), the hydrochloride salt of Buspirone which is an azapirone anolog, is a potent serotonergic 5HT1A receptor agonist with anti-psychotic effects.
Dihydroergotamine Mesylate (DHE; Migranal) is a naturally occuring ergot alkaloid widely used to treat migraines.
Lorcaserin HCl (Belviq Xr; APD-356; APD356; Lorqess), the hydrochloride salt of Lorcaserin which is a marketed weight-loss drug, is a potent and selective full agonist of human 5-HT2C (serotonin) receptor with Ki of 15 nM.
Geissoschizine methyl ether, a naturally occuring indole alkaloid extrated from Uncaria hook, is a major active component of Yokukansan with psychotropic effects. Geissoschizine methyl ether is potent 5-HT1A receptor agonist, and also a potent acetylcholinesterase (AChE) inhibitor.
BRL-15572 (BRL-15,572; BRL-15572; BRL 15,572; BRL15,572) dihydrochloride salt is a potent and selective 5-HT1D receptor antagonist with important biological activity.