Lorcaserin HCl

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
250mg	$850	Check With Us
500mg	$1350	Check With Us
1g	$2025	Check With Us

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Cat #: V1032 CAS #: 846589-98-8 Purity ≥ 98%

Description: Lorcaserin HCl (Belviq Xr; APD-356; APD356; Lorqess), the hydrochloride salt of Lorcaserin which is a marketed weight-loss drug, is a potent and selective full agonist of human 5-HT2C (serotonin) receptor with Ki of 15 nM.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	232.15
Molecular Formula	C11H14ClN.HCl
CAS No.	846589-98-8
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 46 mg/mL (198.1 mM)r
	Water: 46 mg/mL (198.1 mM)r
	Ethanol: 46 mg/mL (198.1 mM)
Synonyms	APD 356; Lorcaserin hydrochloride; Belviq Xr; Lorcaserin HCl; APD-356; APD356; Lorqess.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	4.3076 mL	21.5378 mL	43.0756 mL	86.1512 mL
5mM	0.8615 mL	4.3076 mL	8.6151 mL	17.2302 mL
10mM	0.4308 mL	2.1538 mL	4.3076 mL	8.6151 mL
20mM	0.2154 mL	1.0769 mL	2.1538 mL	4.3076 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.