LY-344864 HCl, the hydrochloride salt of LY344864, is a novel, potent and selective receptor agonist of 5-HT1F with Ki of 6 nM.

Amitriptyline (Elavil; Tryptanol; Amitriptylin; Damilen; Triptanol), a tricyclic antidepressant (TCA), is an inhibitor of serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with potential anti-depressive activity.

Serotonin HCl (5-HT HCl; 5-Hydroxytryptamine), the hydrochloride salt of Serotonin, is an endogenous monoamine neurotransmitter found in the brain and also an endogenous agonist of 5-HT receptor.

Ketanserin tartrate (R-41468; Vulketan) is an aprroved antihypertensive drug, acting as a potent and specific 5-HT2A serotonin receptor antagonist with a Ki of 2.5 nM for rat and human 5-HT2A.

WAY-100635 maleate (WAY 100635; WAY100635), the maleate salt of WAY-100635, is a novel, potent and selective antagonist of serotonin 5-HT1A receptor with important biological activity.

GR127935 HCl (GR-127935; GR 127935) is a novel, highly potent and selective 5-HT1B/1D receptor antagonist with pKis of 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors.

Eucalyptol (1,8-epoxy-p-Menthane; Cineole; 1,8-Cineole; NSC-617) is an organic compound and a colorless liquid, acting an inhibitor of 5-HT3 receptor ,potassium channel, TNF-α and IL-1β.

Lamotrigine (Lamictal, BW 430C; BW430C; Crisomet, Lamictin, Lamitor), an approved anti-convulsant drug used in the treatment of epilepsy and bipolar disorder, is an inhibitor of 5-HT with IC50 of 240 μM and 474 μM in human platelets and rat brain synaptosomes.

Olanzapine (formerly LY-170052, LY 170052, Zyprexa, Zolafren), a thienobenzodiazepine analog, is an approved atypical antipsychotic drug with high affinity for 5-HT2 serotonin and D2 dopamine receptor.

Fluoxetine HCl (LY-110140; Lilly-110140; Prozac, Sarafem, Animex-On, Pulvules, Eufor, Portal), the HCl salt of fluoxetine, is a potent and selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane with anti-depressant activity.