Lumateperone tosylate(also known as ITI-722 ,ITI-007,Lumateperone toluenesulfonic acid or Lumateperone PTSA salt ), is a 5-HT2A receptor antagonist.

Desvenlafaxine (WY-45233; WY45233; brand names Pristiq, Desfax), the active metabolite of the antidepressant venlafaxine, is a potent inhibitor/antagonist of the reuptake of serotonin (5-HT) transporter and norepinephrine (NE) transporter with Ki of 40.2 nM and 558.4 nM respectively.

Sumatriptan Succinate (GR-43175; GR43175; Sumatran; Sumax), an approved triptan sulfa drug and a sulfonamide compound, is a selective 5-HT1 receptor agonist used for the treatment of migraine headaches.

Asenapine (Org5222; Org-5222; HSDB-8061; HSDB8061; Saphris and Sycrest), an atypical antipsychotic, is a potent and high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors.

Aripiprazole D8 is the octa-deuterated form of Aripiprazole (OPC-14597; trade name Abilify) which is a 5-HT1A receptor partial agonist (Ki = 4.2 nM) and an approved atypical antipsychotic drug.

Pardoprunox (formerly known as SLV-308, DU-126891 or SME-308) is novel & potent dopamine D2/5-HT1A receptor agonist that has the potential for the treatment of Parkinson’s disease.

Lasmiditan (formerly known as COL-144 and LY-573144) is a novel and selective 5-HT(1F) receptor agonist with Ki of 2.1 nM versus Ki of 1043 nM and 1357 nM at the 5-HT(1B) and 5-HT(1D) receptors, respectively.

Roluperidone (formerly also known as CYR-101, MIN-101, CYR101, and MT-210) is a novel and potent cyclic amide derivative with-schizophrenia effects.

RS-127445 (RS 127445; RS127445) is a novel, potent, selective, and orally bioavailable 5-HT2B receptor antagonist with important biological activity.

Lu AE58054 hydrochloride (also known as Idalopirdine hydrochloride) is potent and selective antagonist of the 5-HT(6) receptor with Ki value of 0.83 nM.