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Primidone (NCI-C56360)

This product is for research use only, not for human use. We do not sell to patients.

Primidone (NCI-C56360)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5g$250Check With Us
10g$400Check With Us
20g$600Check With Us
email: [email protected]        [email protected]

Cat #: V1669 CAS #: 125-33-7 Purity ≥ 98%

Description: Primidone (also known as NCI-C56360; NCIC56360; Mylepsinum; Mizodin; Primaclone; Mysoline; Resimatil), an analog of phenobarbital, is an anticonvulsant of the barbiturate class.

References: Kevin Kwong, et al. Voltage-gated sodium channels. Curr Opin Pharmacol. 2015 Jun;22:131-9

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Molecular Weight (MW)218.25
Molecular FormulaC12H14N2O2
CAS No.125-33-7
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 44 mg/mL (201.6 mM)r
Water: <1 mg/mLr
Ethanol: 3 mg/mL (13.7 mM)
SynonymsNCI-C56360; Primidone; Primaclone; NCIC56360; Mylepsinum; Mizodin; Mysoline; NCI C56360; Resimatil;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.5819 mL22.9095 mL45.8190 mL91.6380 mL
5mM0.9164 mL4.5819 mL9.1638 mL18.3276 mL
10mM0.4582 mL2.2910 mL4.5819 mL9.1638 mL
20mM0.2291 mL1.1455 mL2.2910 mL4.5819 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.