This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 500mg | $450 | Check With Us |
| 1g | $750 | Check With Us |
| 5g | $2025 | Check With Us |
: Cat #: V28566 CAS #: 104632-25-9 Purity ≥ 99%
Description: Pramipexole 2HCl (also known as SND 919), an agonist of the Gαi-linked dopamine receptors D2, D3, and D4, is a potent dopamine agonist of the non-ergoline class that is used for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS).
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- Related Biological Data
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| Molecular Weight (MW) | 284.25 |
|---|---|
| Molecular Formula | C10H19Cl2N3S |
| CAS No. | 104632-25-9 |
| Protocol | In Vivo | Pramipexole dihydrochloride (0.25-1 mg/kg; i.p.) significantly reduces the infarction volume in animals. Pramipexole dihydrochloride improves neurological recovery. Pramipexole dihydrochloride prevents ischemic cell death via mitochondrial pathways in ischemic stroke |
|---|---|---|
| Animal model | Male Wistar rats weighing 250-300 g (16-18 weeks old) | |
| Dosages | 0.25 mg/kg, 1 mg/kg | |
| Administration | Intraperitoneal injection, at 1 hour, 6 hours, 12 hours, 18 hours post-occlusion |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.5180 mL | 17.5901 mL | 35.1803 mL | 70.3606 mL |
| 5mM | 0.7036 mL | 3.5180 mL | 7.0361 mL | 14.0721 mL |
| 10mM | 0.3518 mL | 1.7590 mL | 3.5180 mL | 7.0361 mL |
| 20mM | 0.1759 mL | 0.8795 mL | 1.7590 mL | 3.5180 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.