Phenytoin Sodium

This product is for research use only, not for human use. We do not sell to patients.

Phenytoin Sodium
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10g$165Check With Us
100g$650Check With Us
200mg$975Check With Us

Cat #: V1647 CAS #: 630-93-3 Purity ≥ 98%

Description: Phenytoin Sodium (also known as 5,5-Diphenylhydantoin; Diphenylhydantoin Sodium; Diphantoine), the sodium salt of Phenytoin, is an inactive voltage-gated sodium channel stabilizer.

References: Michaela Nelson, et al. The sodium channel-blocking antiepileptic drug phenytoin inhibits breast tumour growth and metastasis. Mol Cancer. 2015 Jan 27;14(1):13.

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Molecular Weight (MW)274.25
Molecular FormulaC15H11N2NaO2
CAS No.630-93-3
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 32 mg/mL (116.7 mM)rr
Water: 3 mg/mL (10.9 mM)rr
Ethanol: 11 mg/mL (40.1 mM)
SynonymsDiphenylhydantoin Sodium; Dilantin sodium; 5,5-Diphenylhydantoin sodium; Diphantoine
ProtocolIn VivoPhenytoin sodium (5,5-Diphenylhydantoin sodium salt; 60 mg/kg; daily; 28 days ) reduces tumour growth in six week-old female Rag2-/-Il2rg-/-mice with MDA-MB-231 cells
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.6463 mL18.2315 mL36.4631 mL72.9262 mL
5mM0.7293 mL3.6463 mL7.2926 mL14.5852 mL
10mM0.3646 mL1.8232 mL3.6463 mL7.2926 mL
20mM0.1823 mL0.9116 mL1.8232 mL3.6463 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.