Phenothiazine (NSC2037; ENT38)

This product is for research use only, not for human use. We do not sell to patients.

Phenothiazine (NSC2037; ENT38)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10g$150Check With Us
25g$250Check With Us
50g$375Check With Us

Cat #: V1256 CAS #: 92-84-2 Purity ≥ 98%

Description: Phenothiazine (NSC 2037; ENT38; ENT 38; NSC-2037) is a potent dopamine-2 (D2) receptor antagonist used as antipsychotic medications for the treatment of schizophrenia and manifestations of psychotic disorders.

References: Mitchell SC, et, al. The toxicity of phenothiazine. Drug Metabol Drug Interact. 1994;11(3):201-35.

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Product Promise

Promise
Molecular Weight (MW)199.27
Molecular FormulaC12H9NS
CAS No.92-84-2
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 40 mg/mL (200.7 mM)r
Water: <1 mg/mLr
Ethanol: <1 mg/mL
Solubility In VivoChemical Name: 10H-Phenothiazine InChi Key: WJFKNYWRSNBZNX-UHFFFAOYSA-N InChi Code: InChI=1S/C12H9NS/c1-3-7-11-9(5-1)13-10-6-2-4-8-12(10)14-11/h1-8,13H SMILES Code: C12=CC=CC=C1NC3=C(C=CC=C3)S2
SynonymsENT-38; Phenothiazine; NSC 2037; ENT38; ENT 38; NSC-2037 NSC2037
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM5.0183 mL25.0916 mL50.1832 mL100.3663 mL
5mM1.0037 mL5.0183 mL10.0366 mL20.0733 mL
10mM0.5018 mL2.5092 mL5.0183 mL10.0366 mL
20mM0.2509 mL1.2546 mL2.5092 mL5.0183 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.