Penciclovir
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $850 | Check With Us |
| 1g | $1100 | Check With Us |
| 5g | $2785 | Check With Us |
: Cat #: V18143 CAS #: 39809-25-1 Purity ≥ 99%
Description: Penciclovir (BRL-39123) is a guanosine analogue used as an antiviral drug for the treatment of various herpesvirus infections.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 253.26 |
|---|---|
| Molecular Formula | C10H15N5O3 |
| CAS No. | 39809-25-1 |
| SMILES Code | C1=NC2=C(N1CCC(CO)CO)NC(=NC2=O)N |
| Synonyms | Penciclovir; Denavir, Vectavir and Fenivir.; BRL-39123; BRL 39123; BRL39123; VSA 671; VSA671; VSA-671; |
| Protocol | In Vitro | Penciclovir (0-100 µg/ml) shows no-toxic to uninfected human cells. Penciclovir (0-100 µg/ml) shows anti-herpesvirus activity with EC50s of 0.5, 0.8, 2.4, 52, 100, 1.2, 1.6, 0.9, >100 µg/ml for HSV-1 (HFEM), HSV-2 (MS), VZV (Ellen), CMV (AD-169), BHV-1 (Oxford 1964), BHV-2 (New York 1), EHV-1(Quai Hals), FHV-1 (B927), SVV, respectively. |
|---|---|---|
| In Vivo | Penciclovir (100 mg/kg; s.c.; daily for 5 days) preventes mortality in mouse. | |
| Animal model | Three-week-old female Balb/c mice |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.9485 mL | 19.7426 mL | 39.4851 mL | 78.9702 mL |
| 5mM | 0.7897 mL | 3.9485 mL | 7.8970 mL | 15.7940 mL |
| 10mM | 0.3949 mL | 1.9743 mL | 3.9485 mL | 7.8970 mL |
| 20mM | 0.1974 mL | 0.9871 mL | 1.9743 mL | 3.9485 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.