2-DG (2-Deoxy-D-arabinohexose) is a potnet inhibitor of glycolysis via its actions on hexokinase, the rate limiting step of glycolysis.
Famciclovir (also known as BRL 42810) is a guanine class of antiviral drug used for the treatment of various herpesvirus infections, such as herpes zoster (shingles).
Pritelivir mesylate (formerly known as AIC-316, BAY-571293), the mesylate salt of Pritelivir, is a novel and potent helicase primase inhibitor with antiviral effects against herpes simplex virus (HSV). It inhibits HSV with IC50 of 20 nM for both HSV-1 and HSV-2. It represents a new class of potent inhibitors of HSV that target the virus […]
Ganciclovir hydrate is a novel and potent antiviral medication used to treat or prevent cytomegalovirus (CMV) infections.
Amenamevir (formerly ASP2151; ASP-2151) is a HSV (herpes simplex virus) helicase-primase inhibitor with potent antiviral activity against HSVs with EC50 of 14 ng/mL. It an antiviral drug used for the treatment of shingles, acting as an inhibitor of the zoster virus’s helicase–primase complex. Amenamevir was approved in Japan for the treatment of shingles in 2017. […]
Penciclovir (BRL-39123) is a guanosine analogue used as an antiviral drug for the treatment of various herpesvirus infections.
As an anti-viral agent against HSV and varicella-zoster virus (VZV).
5-Nitrobarbituric acid is a herpes simplex virus type-1 (HSV-1) inhibitor with an IC50 of 1.7 μM.
5-Hydroxymethyldeoxyuridine is a nucleoside analog with potent anticancer and antiviral activities. It inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8.5 and 4 μM, respectively) and multiple human leukemia cell lines (IC50s = 1.7-5.8 μM).