Parecoxib (SC 69124)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $420 | Check With Us |
| 1g | $600 | Check With Us |
| 5g | $1515 | Check With Us |
: Cat #: V31967 CAS #: 198470-84-7 Purity ≥ 99%
Description: Parecoxib (SC69124A; Dynastat) is a selective cyclooxygenase-2 (COX-2) inhibitor with the potential for treating postoperative pain in adults.
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| Molecular Weight (MW) | 370.42 |
|---|---|
| Molecular Formula | C19H18N2O4S |
| CAS No. | 198470-84-7 |
| SMILES Code | CCC(NS(=O)(C1=CC=C(C2=C(C)ON=C2C3=CC=CC=C3)C=C1)=O)=O |
| Synonyms | SC69124; SC-69124; SC 69124; Parecoxib Free Base; |
| Protocol | In Vitro | Parecoxib (0-200 μM; 24-48 hours) inhibits the cell proliferation of GBM cells in a dose-dependent manner in GBM cells. |
|---|---|---|
| In Vivo | Parecoxib (intraperitoneal injection; 2.5, 5.0 or 10 mg/kg; once a day; 21 days) does not affect locomotor activity in the elevated plus-maze test, and Parecoxib at 5 and 10 mg/kg shows higher levels of percentage of time spent in the open arms. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.6996 mL | 13.4982 mL | 26.9964 mL | 53.9928 mL |
| 5mM | 0.5399 mL | 2.6996 mL | 5.3993 mL | 10.7986 mL |
| 10mM | 0.2700 mL | 1.3498 mL | 2.6996 mL | 5.3993 mL |
| 20mM | 0.1350 mL | 0.6749 mL | 1.3498 mL | 2.6996 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.