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Palonosetron HCl (RS25233-197; Aloxi)

This product is for research use only, not for human use. We do not sell to patients.

Palonosetron HCl (RS25233-197; Aloxi)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$750Check With Us
5g$1350Check With Us
10g$2025Check With Us
email: [email protected]        [email protected]

Cat #: V1022 CAS #: 135729-62-3 Purity ≥ 98%

Description: Palonosetron HCl (formerly RS-25259, RS-25259, RS 25259 197, RS-25259197; trade names: Aloxi and Akynzeo), an approved antiemetic drug, is a potent 5-HT3 antagonist that has been used in the prevention and treatment of chemotherapy-induced nausea and vomiting.

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Molecular Weight (MW)332.87
Molecular FormulaC19H24N2O.HCl
CAS No.135729-62-3
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: <1 mg/mLr
Water: 67 mg/mL (201.3 mM)r
Ethanol: <1 mg/mL
SynonymsRS-25233-197; RS25233-198; RS 25259, RS 25259 197; Palonosetron hydrochloride; RS 25233-197; RS25233-197; RS-25233-198; RS 25233-198; RS-25259-197; US brand name: Aloxi and Akynzeo
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.0042 mL15.0209 mL30.0418 mL60.0835 mL
5mM0.6008 mL3.0042 mL6.0084 mL12.0167 mL
10mM0.3004 mL1.5021 mL3.0042 mL6.0084 mL
20mM0.1502 mL0.7510 mL1.5021 mL3.0042 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.