Paliperidone

This product is for research use only, not for human use. We do not sell to patients.

Paliperidone
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1g$450Check With Us
2g$650Check With Us
5g$980Check With Us

Cat #: V1260 CAS #: 144598-75-4 Purity ≥ 98%

Description: Paliperidone (Invega; Invega Sustenna; Invega Sustenna; 9-hydroxyrisperidone), the main active metabolite of Risperidone, is a potent serotonin-2A and dopamine-2 receptor antagonist used for the treatment of schizophrenia.

References: Mauri MC, Paletta S, Maffini M, et al. Clinical pharmacology of atypical antipsychotics: an update. EXCLI J. 2014;13:1163-1191. Published 2014 Oct 13.

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Product Promise

Promise
Molecular Weight (MW)426.48
Molecular FormulaC23H27FN4O3
CAS No.144598-75-4
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 4 mg/mL (9.4 mM)r
Water: <1 mg/mLr
Ethanol: <1 mg/mL
Synonyms9-Hydroxyrisperidone; Invega; Paliperidone; 9-OH-risperidone; Invega Sustenna; Invega Sustenna; paliperidone
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3448 mL11.7239 mL23.4478 mL46.8955 mL
5mM0.4690 mL2.3448 mL4.6896 mL9.3791 mL
10mM0.2345 mL1.1724 mL2.3448 mL4.6896 mL
20mM0.1172 mL0.5862 mL1.1724 mL2.3448 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.