PACAP 1-38
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 50mg | $1850 | Check With Us |
| 100mg | $2775 | Check With Us |
| 200mg | $4160 | Check With Us |
: Cat #: V2752 CAS #: 137061-48-4 Purity ≥ 98%
Description: PACAP 1-38 is a highly potent agonist of the PACAP (Pituitary adenylate cyclase-activating polypeptide) receptor with Kd of 100 pM.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 4534.26 |
|---|---|
| Molecular Formula | C203H331N63O53S |
| CAS No. | 137061-48-4 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: N/Ar |
| Water: 100 mg/mL (22.05 mM)r | |
| Ethanol: N/A | |
| Solubility In Vivo | N/A |
| Synonyms | PACAP (1-38), human, ovine, rat; Pituitary Adenylate Cyclase Activating Polypeptide 38 |
| Protocol | In Vitro | PACAP (1-38), human, ovine, rat is a fragment of pituitary adenylate cyclase activating polypeptide. PACAP (1-38) shows high affinity for PACAP specific (PAC1) receptor in membranes from various tissues including the endocrine pancreas. In vitro, PACAP (1-38) relaxes guinea-pig and rabbit tracheal smooth muscle precontracted by histamine and by acetylcholine. PACAP (1-38) also increases adenosine 3':5'-cyclic monophosphate (cyclic AMP) in tracheal smooth muscle, providing a possible mechanism for the relaxant effect of PACAP (1-38) |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 0.2205 mL | 1.1027 mL | 2.2054 mL | 4.4109 mL |
| 5mM | 0.0441 mL | 0.2205 mL | 0.4411 mL | 0.8822 mL |
| 10mM | 0.0221 mL | 0.1103 mL | 0.2205 mL | 0.4411 mL |
| 20mM | 0.0110 mL | 0.0551 mL | 0.1103 mL | 0.2205 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.