Oxiracetam (ISF 2522)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
1g	$250	Check With Us
2g	$400	Check With Us
5g	$630	Check With Us

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Cat #: V1934 CAS #: 62613-82-5 Purity ≥ 98%

Description: Oxiracetam (also known as ISF 2522), a novel cyclic derivative of gamma-aminobutyric acid (GABA) which acts as a positive allosteric modulator of the AMPA receptors, is widely used as a nootropic drug to improve memory and learning in patients with cognitive impairments.

References: Li W, et al. (S)-Oxiracetam is the Active Ingredient in Oxiracetam that Alleviates the Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats. Sci Rep. 2017 Aug 30;7(1):10052.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	158.16
Molecular Formula	C6H10N2O3
CAS No.	62613-82-5
Storage	-20℃ for 3 years in powder formrr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 31 mg/mL (196.0 mM)rr
	Water: 31 mg/mL (196.0 mM)rr
	Ethanol: <1 mg/mL
SMILES Code	O=C(N)CN1C(CC(O)C1)=O
Synonyms	ISF 2522; ISF2522; ISF-2522; Neuractiv; Hydroxypiracetam;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	6.3227 mL	31.6136 mL	63.2271 mL	126.4542 mL
5mM	1.2645 mL	6.3227 mL	12.6454 mL	25.2908 mL
10mM	0.6323 mL	3.1614 mL	6.3227 mL	12.6454 mL
20mM	0.3161 mL	1.5807 mL	3.1614 mL	6.3227 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.