NSC117079

This product is for research use only, not for human use. We do not sell to patients.

NSC117079
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1250To Be Confirmed
500mg$1850To Be Confirmed
1g$2775To Be Confirmed

Cat #: V5022 CAS #: 500363-63-3 Purity ≥ 98%

Description: NSC117079 is a novel and potent PHLPP1 (Pleckstrin homology domain and leucine-rich repeat protein phosphatase 1) inhibitor.

References: Jackson TC, et al. Pharmacological inhibition of pleckstrin homology domain leucine-rich repeat protein phosphatase is neuroprotective: differential effects on astrocytes. J Pharmacol Exp Ther. 2013 Nov;347(2):516-28.

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Molecular Weight (MW)473.48
Molecular FormulaC₂₀H₁₅N₃O₇S₂
CAS No.500363-63-3
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO=S(C(C(N)=C1C2=O)=CC(NC3=CC=CC(S(=O)(N)=O)=C3)=C1C(C4=C2C=CC=C4)=O)(O)=O
SynonymsNSC-117079; NSC 117079; NSC117079
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1120 mL10.5601 mL21.1202 mL42.2404 mL
5mM0.4224 mL2.1120 mL4.2240 mL8.4481 mL
10mM0.2112 mL1.0560 mL2.1120 mL4.2240 mL
20mM0.1056 mL0.5280 mL1.0560 mL2.1120 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.