BVT948 (BVT-948) is a novel and potent protein tyrosine phosphatases (PTP) inhibitor with IC50 of 0.09 – 1.7 μM.
BR-1 is a novel and potent PRL-3 inhibitor (IC50 = 0.9 μM) with anticancer activity.
BCI is a novel small-molecule and allosteric inhibitor of DUSP6 (dual-specificity phosphatase 6) with IC50 of 12.3 uM.
PTP1B-IN-2 is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor.
NSC-95397 is a novel, potent, and selective CDC25B inhibitor which inhibits influenza A virus replication in dose-dependent fashion.
TPI-1 (full name: Tyrosine Phosphatase Inhibitor 1) is an inhibitor of SHP-1 (Src homology region 2 domain-containing phosphatase 1) with an IC50 of 40 nM.
NSC117079 is a novel and potent PHLPP1 (Pleckstrin homology domain and leucine-rich repeat protein phosphatase 1) inhibitor.
Tacrolimus (formerly also known as FK-506), a macrocyclic lactone isolated from the culture broth of a strain of Streptomyces tsukubaensis, is an immunosuppressive agent used mainly after allogeneic organ transplant to reduce the activity of the patient’s immune system and to lower the risk of organ rejection.
Raphin1 is a novel and potent inhibitor of the regulatory phosphatase PPP1R15B (R15B).
(-)-p-Bromotetramisole Oxalate (also known as L-p-Bromotetramisole Oxalate) is a potent, cell-permeable and non-specific alkaline phosphatase inhibitor.