NS-11021
This product is for research use only, not for human use. We do not sell to patients.
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Size | Price | Stock |
---|---|---|
100mg | $720 | Check With Us |
250mg | $1250 | Check With Us |
500mg | $1875 | Check With Us |
Cat #: V11738 CAS #: 956014-19-0 Purity ≥ 98%
Description: NS-11021 is a novel, potent and selective activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1).
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Molecular Weight (MW) | 511.2444 |
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Molecular Formula | C16H9BrF6N6S |
CAS No. | 956014-19-0 |
Synonyms | NS-11021; NS 11021; NS11021. |
Protocol | In Vitro | NS 11021 (1-30 μM) increases the current of hKCa1.1 from 2 μA to 4 μA at the concentration of 3 μM and can activate the hKCa1.1 expression channel in a dose-dependent manner in X. laevis oocytes |
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These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 1.9560 mL | 9.7801 mL | 19.5601 mL | 39.1202 mL |
5mM | 0.3912 mL | 1.9560 mL | 3.9120 mL | 7.8240 mL |
10mM | 0.1956 mL | 0.9780 mL | 1.9560 mL | 3.9120 mL |
20mM | 0.0978 mL | 0.4890 mL | 0.9780 mL | 1.9560 mL |
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
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Step Two: Enter the in vivo formulation
%DMSO
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%Tween 80
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%ddH2O
Calculation Results:
Working concentration:
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Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
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mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.