Nolatrexed 2HCl

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Nolatrexed 2HCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$650To Be Confirmed
250mg$1250To Be Confirmed
500mg$1875To Be Confirmed

Cat #: V16389 CAS #: 152946-68-4 Purity ≥ 99%

Description: Nolatrexed dHCl (AG-337 dihydrochloride; thymitaq), a folate analog, is a novel and potent thymidylate synthase inhibitor with potential anticancer activity.

References: Webber S, et al. AG337, a novel lipophilic thymidylate synthase inhibitor: in vitro and in vivo preclinical studies. Cancer Chemother Pharmacol. 1996;37(6):509-17.

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Molecular Weight (MW)C14H14Cl2N4OS
Molecular Formula357.26
CAS No.152946-68-4
SynonymsNolatrexed 2HCl
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.