NM-107
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $330 | Check With Us |
| 250mg | $600 | Check With Us |
| 500mg | $900 | Check With Us |
: Cat #: V14696 CAS #: 20724-73-6 Purity ≥ 99%
Description: NM-107 (2'-C-Methylcytidine; 2'CMeC; 2'-C-MeC; mCyd; 2CMC) is a novel, potent and selective anti-viral agent acting as an inhibitor of the hepatitis C virus (HCV) NS5B polymerase.
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| Molecular Weight (MW) | 257.24 |
|---|---|
| Molecular Formula | C10H15N3O5 |
| CAS No. | 20724-73-6 |
| SMILES Code | OC[C@@H]1[C@H]([C@@]([C@H](N2C(N=C(C=C2)N)=O)O1)(C)O)O <br/> |
| Synonyms | 2'-C-MeC; 2-CMC; mCyd ; 2'CMeC; 2CMC; NM-107; NM 107; NM107; 2'-C-Methylcytidine; |
| Protocol | In Vitro | NM107 (25 μM; 24 hours; Huh7-1 cells and cell culture-propagated HCV) treatment decreases extracellular viral titers and intracellular RNA levels. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.8874 mL | 19.4371 mL | 38.8742 mL | 77.7484 mL |
| 5mM | 0.7775 mL | 3.8874 mL | 7.7748 mL | 15.5497 mL |
| 10mM | 0.3887 mL | 1.9437 mL | 3.8874 mL | 7.7748 mL |
| 20mM | 0.1944 mL | 0.9719 mL | 1.9437 mL | 3.8874 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Volume
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Molecular Weight*
The dilution calculator equation
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Volume(start)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
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V1
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.