Nimbolide
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $3260 | Check With Us |
| 200mg | $4890 | Check With Us |
| 500mg | $8250 | Check With Us |
: Cat #: V6034 CAS #: 25990-37-8 Purity ≥ 99%
Description: Nimbolide is a naturally occuring triterpene/limonoid isolated from the leaves and flowers of neem (Azadirachta indica L), acting as an inhibitor of pancreatic cancer growth and metastasis through ROS-mediated apoptosis.
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- Physicochemical and Storage Information
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| Molecular Weight (MW) | 466.52 |
|---|---|
| Molecular Formula | C27H30O7 |
| CAS No. | 25990-37-8 |
| SMILES Code | CC1=C2[C@H](O[C@@H]3[C@H](O4)[C@@H]5[C@@](C(C=C[C@@]5(C)C4=O)=O)(C)[C@@H](CC(OC)=O)[C@]23C)C[C@H]1C6=COC=C6 |
| Synonyms | Nimbolide |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.1435 mL | 10.7177 mL | 21.4353 mL | 42.8706 mL |
| 5mM | 0.4287 mL | 2.1435 mL | 4.2871 mL | 8.5741 mL |
| 10mM | 0.2144 mL | 1.0718 mL | 2.1435 mL | 4.2871 mL |
| 20mM | 0.1072 mL | 0.5359 mL | 1.0718 mL | 2.1435 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.