Neochlorogenic acid
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $1100 | Check With Us |
| 1g | $1650 | Check With Us |
| 5g | $4175 | Check With Us |
: Cat #: V28831 CAS #: 906-33-2 Purity ≥ 99%
Description: Neochlorogenic acid is a natural polyphenolic compound with anti-inflammatory activity.
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- Related Biological Data
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| Molecular Weight (MW) | 354.31 |
|---|---|
| Molecular Formula | C16H18O9 |
| CAS No. | 906-33-2 |
| Synonyms | 5-O-Caffeoylquinic acid; Neochlorogenic acid; trans-5-O-Caffeoylquinic acid; Neochlorogenate; |
| Protocol | In Vitro | Neochlorogenic acid (NCA) shows a reduction of lipopolysaccharide (LPS)-induced NO production by suppressing iNOS and COX-2 protein expression and production of pro-inflammatory cytokines, such as TNF-α and IL-1β, in BV2 microglia cells. In addition, phosphorylated p38 MAPK and NF-κB p65 are also inhibited by Neochlorogenic acid in activated microglia. iNOS and COX-2 levels are increased in LPS-induced BV2 cells, but this increase is significantly inhibited after treatment with 50 and 100 μM Neochlorogenic acid. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.8224 mL | 14.1119 mL | 28.2239 mL | 56.4477 mL |
| 5mM | 0.5645 mL | 2.8224 mL | 5.6448 mL | 11.2895 mL |
| 10mM | 0.2822 mL | 1.4112 mL | 2.8224 mL | 5.6448 mL |
| 20mM | 0.1411 mL | 0.7056 mL | 1.4112 mL | 2.8224 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.