Nefiracetam (DM9384; DZL-221)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $290 | Check With Us |
| 2g | $520 | Check With Us |
| 5g | $820 | Check With Us |
: Cat #: V1288 CAS #: 77191-36-7 Purity ≥ 98%
Description: Nefiracetam (DZL-221; DM9384; DZL221; DM 9384; Translon) is a potent GABAergic, cholinergic, and monoaminergic neuronal system enhancer for Ro 5-4864-induced convulsions.
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- Physicochemical and Storage Information
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- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 246.3 |
|---|---|
| Molecular Formula | C14H18N2O2 |
| CAS No. | 77191-36-7 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 49 mg/mL (198.9 mM)r |
| Water: 5 mg/mL (20.3 mM)r | |
| Ethanol: 49 mg/mL (198.9 mM) | |
| Solubility In Vivo | Chemical Name: N-(2,6-dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide InChi Key: NGHTXZCKLWZPGK-UHFFFAOYSA-N InChi Code: InChI=1S/C14H18N2O2/c1-10-5-3-6-11(2)14(10)15-12(17)9-16-8-4-7-13(16)18/h3,5-6H,4,7-9H2,1-2H3,(H,15,17) SMILES Code: O=C(NC1=C(C)C=CC=C1C)CN2C(CCC2)=O |
| Synonyms | DZL 221; DM-9384; DZL-221; DM9384; DZL221; DM 9384; Translon |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.0601 mL | 20.3004 mL | 40.6009 mL | 81.2018 mL |
| 5mM | 0.8120 mL | 4.0601 mL | 8.1202 mL | 16.2404 mL |
| 10mM | 0.4060 mL | 2.0300 mL | 4.0601 mL | 8.1202 mL |
| 20mM | 0.2030 mL | 1.0150 mL | 2.0300 mL | 4.0601 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.