Mycophenolate Mofetil

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
5g	$480	Check With Us
10g	$800	Check With Us
20g	$1200	Check With Us

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Cat #: V0852 CAS #: 128794-94-5; Purity ≥ 99%

Description: Mycophenolate Mofetil (Cellcept, Mycophenolic acid, Myfortic, RS-61443), an antimetabolite immunosuppressant, is a potent, non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively.

References: Simmons WD, et al. Preliminary risk-benefit assessment of mycophenolate mofetil in transplant rejection. Drug Saf. 1997;17(2):75-92.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	433.49
Molecular Formula	C23H31NO7
CAS No.	128794-94-5;
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 86 mg/mL (198.4 mM)r
	Water: <1 mg/mLr
	Ethanol: <1 mg/mL
Solubility In Vivo	0.5% methylcellulose: 20 mg/mL
SMILES Code	O=C(OCCN1CCOCC1)CC/C(C)=C/CC2=C(OC)C(C)=C3COC(C3=C2O)=O
Synonyms	RS61443; Mycophenolic acid, Mycophenolate mofetil, Cellcept, Myfortic, RS-61443; Mycophenolate mofetil (free acid);

Protocol	In Vitro	The inosine monophosphate dehydrogenase is an important enzyme in the de novo synthesis of guanosine nucleotides in T and B lymphocytes.

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.3069 mL	11.5343 mL	23.0686 mL	46.1372 mL
5mM	0.4614 mL	2.3069 mL	4.6137 mL	9.2274 mL
10mM	0.2307 mL	1.1534 mL	2.3069 mL	4.6137 mL
20mM	0.1153 mL	0.5767 mL	1.1534 mL	2.3069 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.