SW033291 (SW-033291; SW 033291) is a selective and high affinity inhibitor of the prostaglandin-degrading enzyme 15-PGD (15-hydroxyprostaglandin dehydrogenase) with potential kidney and liver protective effects.
Brequinar sodium (also known as DUP785; NSC-368390), a synthetic quinolinecarboxylic acid analog, is a novel and potent inhibitor of dihydroorotate dehydrogenase with potent activities against a broad spectrum of viruses and antineoplastic properties.
Enoxolone (Glycyrrhetin; NSC 35347; Enoxolone; Glycyrrhetic acid; BRN-2229654; NSC-35347) is a novel, potent, pentacyclic triterpenoid derivative of the beta-amyrin type with potential liver-protecting effects.
(R,S)-Ivosidenib (AG120; RG120; AG-120; RG-120; Tibsovo), the racemic mixture of Ivosidenib, is an orally bioavailable and small molecule IDH1 inhibitor that inhibits mutated cytosolic isocitrate dehydrogenase 1 (IDH1).
Ammonium Glycyrrhizinate (AMGZ, Glycyram; Monoammonium glycyrrhizinate), a triterpenoid saponin analog, is responsible for the sweet-tasting of Glycyrrhiza glabra root.
Olutasidenib (FT-2102) is a novel, highly potent and selective small molecue inhibitor of mutant Isocitrate dehydrogenase 1 (IDH1) with the potential to be used in the treatment of acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).
(R)-GNE-140, the S-enantiomer of GNE-140, is a novel and potent lactate dehydrogenase (LDHA) inhibitor with potential anticancer activity.
Gimeracil (chlorodihydroxypyridine; CDHP; Gimestat), a pyridine/pyridone analog and an approved anticancer drug, is a potent inhibitor of the dihydropyrimidine dehydrogenase (DPYD) enzyme with potential anti-neoplastic activity.
Vidofludimus (4SC101; SC-12267; SC12267, 4SC-101; 4SC 101; SC 12267) is a novel, potent and orally bioactive/bioavailable inhibitor of dihydroorotate dehydrogenase (DHODH) with potential anti-inflammatory, immunomodulating and anti-viral activities.
Isovaleramide (NPS-1776; NPS 1776; NPS1776; 3-Methylbutanamide), a natural product found in Valeriana pavonii, is a potent anticonvulsant agent that acts as an inhibitor of alcohol dehydrogenases.