Muramyl Dipeptide
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $950 | Check With Us |
| 500mg | $1500 | Check With Us |
| 1g | $2250 | Check With Us |
: Cat #: V23174 CAS #: 53678-77-6 Purity ≥ 99%
Description: Muramyl Dipeptide (MDP) is a novel and potent NOD2 agonist.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 492.48 |
|---|---|
| Molecular Formula | C19H32N4O11 |
| CAS No. | 53678-77-6 |
| SMILES Code | O=C(N)[C@H](N(CC(O[C@H]1[C@@H]([C@H](O[C@@H]([C@@H]1NC(C)=O)O)CO)O)C)C([C@H](C)N)=O)CCC(O)=O <br/> |
| Synonyms | Ac-muramyl-Ala-D-Glu-NH2; N-Acetylmuramyl-L-alanyl-D-isoglutamine; Muramyl Dipeptide; Adjuvant Peptide; |
| Protocol | In Vitro | Muramyl dipeptide indirectly attenuates osteoclast differentiation through a decreased RANKL/OPG ratio. Muramyl dipeptide (0.1-10 µg/mL; 6 hours) increases mRNA levels of Runx2 in a dose-dependent manner. Muramyl dipeptide (0.1-10 µg/mL; 24 hours) increases protein expression of Runx2 in a dose-dependent manner. |
|---|---|---|
| In Vivo | Muramyl dipeptide (1.25 mg/kg; i.p.; twice) alleviates bone loss induced by osteoporosis. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.0305 mL | 10.1527 mL | 20.3054 mL | 40.6108 mL |
| 5mM | 0.4061 mL | 2.0305 mL | 4.0611 mL | 8.1222 mL |
| 10mM | 0.2031 mL | 1.0153 mL | 2.0305 mL | 4.0611 mL |
| 20mM | 0.1015 mL | 0.5076 mL | 1.0153 mL | 2.0305 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.