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Mosapride Citrate (TAK-370; AS-4370)

This product is for research use only, not for human use. We do not sell to patients.

Mosapride Citrate (TAK-370; AS-4370)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1g$950Check With Us
2g$1450Check With Us
5g$2180Check With Us

Cat #: V0994 CAS #: 112885-42-4 Purity ≥ 98%

Description: Mosapride Citrate (formerly AS-4370; TAK-370 citrate; AS-4370 citrate; TAK 370 citrate) is a novel, potent and selective gastroprokinetic agent that has been used in patients with upper gastrointestinal disorders.

References: Tack J, et al. Systematic review: cardiovascular safety profile of 5-HT(4) agonists developed for gastrointestinal disorders. Aliment Pharmacol Ther. 2012 Apr;35(7):745-67.

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Product Promise

Promise
Molecular Weight (MW)614.02
Molecular FormulaC21H25ClFN3O3.C6H8O7
CAS No.112885-42-4
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 90 mg/mL (146.6 mM)r
Water: <1 mg/mLr
Ethanol: <1 mg/mL
SynonymsAS-4370; TAK-370 citrate; AS-4370 citrate; TAK 370 citrate; AS 4370 citrate; TAK370 citrate; AS4370 citrate
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.6286 mL8.1431 mL16.2861 mL32.5722 mL
5mM0.3257 mL1.6286 mL3.2572 mL6.5144 mL
10mM0.1629 mL0.8143 mL1.6286 mL3.2572 mL
20mM0.0814 mL0.4072 mL0.8143 mL1.6286 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.