ML314

This product is for research use only, not for human use. We do not sell to patients.

ML314
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1020Check With Us
250mg$1750Check With Us
500mg$2625Check With Us

Cat #: V4017 CAS #: 1448895-09-7 Purity ≥ 98%

Description: ML314 is a novel potent small molecule agonist of NTR1 (Neurotensin 1 Receptor) with EC50 of 1.9 μM.

References: Hershberger P, et al. Small Molecule Agonists for the Neurotensin 1 Receptor (NTR1 Agonists). Probe Reports from the NIH Molecular Libraries Program

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Product Promise

Promise
Molecular Weight (MW)420.5
Molecular FormulaC24H28N4O3
CAS No.1448895-09-7
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: ≥ 45mg/mLr
Water: N/Ar
Ethanol: N/A
SMILES CodeCOC1=CC=CC=C1N2CCN(C3=C4C=C(OC)C(OC)=CC4=NC(C5CC5)=N3)CC2
SynonymsML 314; ML-314; ML314
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3781 mL11.8906 mL23.7812 mL47.5624 mL
5mM0.4756 mL2.3781 mL4.7562 mL9.5125 mL
10mM0.2378 mL1.1891 mL2.3781 mL4.7562 mL
20mM0.1189 mL0.5945 mL1.1891 mL2.3781 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.