LM11A-31 HCl
LM11A-31 HCl
Catalog No: V2233
CAS No. (CAS Registry Number): 1243259-19-9
Description:

LM11A-31 HCl，a non-peptide p75NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist，in preventing diabetes-induced BRB breakdown.
ML314
ML314
Catalog No: V4017
CAS No. (CAS Registry Number): 1448895-09-7
Description:

ML314 is a novel potent small molecule agonist of NTR1 (Neurotensin 1 Receptor) with EC50 of 1.9 μM.
AF38469
AF38469
Catalog No: V6718
CAS No. (CAS Registry Number): 1531634-31-7
Description:

AF38469 is a novel, potent, selective, and orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin with an IC50 value of 330 nM.
Talnetant (SB 223412)
Talnetant (SB 223412)
Catalog No: V2091
CAS No. (CAS Registry Number): 174636-32-9
Description:

Talnetant (formerly also known as SB 223412) is a potent and selective NK3 receptor antagonist with ki value of 1.4 nM (hNK-3-CHO); Selectivity studies versus the other neurokinin receptors (hNK-2-CHO and hNK-1-CHO) revealed that Talnetant is about 100-fold selective for the hNK-3 versus hNK-2 receptor, with no affinity for the hNK-1 at concentrations up to […]