MK8722

This product is for research use only, not for human use. We do not sell to patients.

MK8722
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1600Check With Us
500mg$2750Check With Us
1g$4125Check With Us

Cat #: V4287 CAS #: 1394371-71-1 Purity ≥ 98%

Description: MK-8722 (MK8722) is a novel, potent allosteric pan-AMPK activator with anti-diabetic effects.

References: Myers RW, et al. Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiachypertrophy. Science. 2017 Aug 4;357(6350):507-511.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)449.89
Molecular FormulaC24H20ClN3O4
CAS No.1394371-71-1
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeClC1=C2C(NC(O[C@@H]3CO[C@@]4([H])[C@]3([H])OC[C@H]4O)=N2)=NC=C1C5=CC=C(C6=CC=CC=C6)C=C5
SynonymsMK8722; MK 8722; MK-8722
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.2228 mL11.1138 mL22.2277 mL44.4553 mL
5mM0.4446 mL2.2228 mL4.4455 mL8.8911 mL
10mM0.2223 mL1.1114 mL2.2228 mL4.4455 mL
20mM0.1111 mL0.5557 mL1.1114 mL2.2228 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.