Minoxidil
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $400 | Check With Us |
| 1g | $700 | Check With Us |
| 5g | $1950 | Check With Us |
: Cat #: V12383 CAS #: 38304-91-5 Purity ≥ 99%
Description: Minoxidil (U-10858; Loniten; Rogaine) is an antihypertensive agent and vasodilator that has also found usefulness in treatment of hair loss and alopecia areata when applied topically.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 209.2483 |
|---|---|
| Molecular Formula | C9H15N5O |
| CAS No. | 38304-91-5 |
| Protocol | In Vitro | Minoxidil (1-00 µM; 24 hours; RAMEC cells) treatment shows very low cytotoxicities in the whole area of concentrations examined (from 1 µM to 100 µM) |
|---|---|---|
| In Vivo | Minoxidil (0.01 mmoL/kg body weight; intraperitoneal injection; for 3.5 hours; fisher 344 rats) treatment inhibits carrageenan-induced rat paw oedema with an inhibitory potency (49%) | |
| Animal model | Fisher 344 rats (150-200 g) with oedema | |
| Dosages | 0.01 mmol/kg body weight | |
| Administration | Intraperitoneal injection; for 3.5 hours |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.7790 mL | 23.8951 mL | 47.7901 mL | 95.5802 mL |
| 5mM | 0.9558 mL | 4.7790 mL | 9.5580 mL | 19.1160 mL |
| 10mM | 0.4779 mL | 2.3895 mL | 4.7790 mL | 9.5580 mL |
| 20mM | 0.2390 mL | 1.1948 mL | 2.3895 mL | 4.7790 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.