Milnacipran HCl
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $495 | Check With Us |
| 500mg | $899 | Check With Us |
| 1g | $1348 | Check With Us |
: Cat #: V2399 CAS #: 101152-94-7 Purity ≥ 98%
Description: Milnacipran HCl, a medication used in the clinical treatment of fibromyalgia, is a potent inhibitor of both norepinephrine transporter (NET) and norepinephrine transporter (SERT) with IC50 of 77 nM and 420 nM, respectively.
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- Related Biological Data
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| Molecular Weight (MW) | 282.81 |
|---|---|
| Molecular Formula | C15H22N2O.HCl |
| CAS No. | 101152-94-7 |
| Storage | -20℃ for 3 years in powder formrr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 57 mg/mL (201.5 mM)rr |
| Water: 57 mg/mL (201.5 mM)rr | |
| Ethanol: 57 mg/mL (201.5 mM) | |
| SMILES Code | O=C([C@@]1(C2=CC=CC=C2)[C@@H](CN)C1)N(CC)CC |
| Synonyms | Levomilnacipran, F-2207, Ixel, Savella, Dalcipran, Toledomin |
| Protocol | Dosages | 10 and 30 mg/kg, PO |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.5359 mL | 17.6797 mL | 35.3594 mL | 70.7189 mL |
| 5mM | 0.7072 mL | 3.5359 mL | 7.0719 mL | 14.1438 mL |
| 10mM | 0.3536 mL | 1.7680 mL | 3.5359 mL | 7.0719 mL |
| 20mM | 0.1768 mL | 0.8840 mL | 1.7680 mL | 3.5359 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.