Cinchonidine is a natural cinchona alkaloid with antimalarial activity.

Escitalopram (Lu10171; Cipralex; Seroplex; Lu-10171; Citalopram; Lexapro; Cytalopram), the S-isomer/enantiomer of citalopram, is an approved antidepressant drug acting as a selective serotonin (5-HT) reuptake inhibitor (SSRI) with a Ki of 0.89 nM.

Dapoxetine is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.

Dasotraline (formerly known as SEP-225289; SEP-225,289) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) with anti-depressant and anti-ADHD activity.

Venlafaxine free base (Wy-45030; Wy45030; Effexor, Lanvexin, Viepax and Trevilor) is a marketed and arylalkanolamine-based antidepressant acting as an serotonin-norepinephrine reuptake inhibitor (SNRI).

Milnacipran HCl, a medication used in the clinical treatment of fibromyalgia, is a potent inhibitor of both norepinephrine transporter (NET) and norepinephrine transporter (SERT) with IC50 of 77 nM and 420 nM, respectively.

Levomilnacipran (F2695; Fetzima), the S-enantiomer of Milnacipran, is an antidepressant approved for the treatment of major depressive disorder in the United States.