Mevastatin | CAS 73573-88-3

Mevastatin

This product is for research use only, not for human use. We do not sell to patients.

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Size	Price	Stock
5g	$250	Check With Us
10g	$450	Check With Us
20g	$675	Check With Us

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Cat #: V0931 CAS #: 73573-88-3 Purity ≥ 98%

Description: Mevastatin (CS500; ML236B; Mevastatin; Compactin; ML-236B), an approved anti-hyperliperdemic drug of the statin class, is a potent and competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with anti-hyperlipidemic effects.

References: Wächtershäuser A, et al. HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2. Carcinogenesis. 2001 Jul;22(7):1061-7.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	390.51
Molecular Formula	C23H34O5
CAS No.	73573-88-3
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 78 mg/mL (199.7 mM)r
	Water:<1 mg/mLr
	Ethanol: <1 mg/mL
SMILES Code	CC[C@H](C)C(O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(O3)=O)[C@@]12[H])=O
Synonyms	ML-236B; CS-500; CS 500; ML 236B; CS500; ML236B; Mevastatin, Compactin.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.5608 mL	12.8038 mL	25.6075 mL	51.2151 mL
5mM	0.5122 mL	2.5608 mL	5.1215 mL	10.2430 mL
10mM	0.2561 mL	1.2804 mL	2.5608 mL	5.1215 mL
20mM	0.1280 mL	0.6402 mL	1.2804 mL	2.5608 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.