Metoprolol Tartrate

This product is for research use only, not for human use. We do not sell to patients.

Metoprolol Tartrate
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Size Price Stock
10g$450Check With Us
25g$700Check With Us
50g$1050Check With Us

Cat #: V1153 CAS #: 56392-17-7 Purity ≥ 98%

Description: Metoprolol Tartrate (CGP2175E; CGP-2175E; Lanoc; Lopressor; Metomerck; Metop; Selopral; Ritmolol), the tartrate salt of Metoprolol, is a potent and cardioselective β1 receptor blocker with antihypertensive effects.

References: Ulleryd MA, et al. Metoprolol reduces proinflammatory cytokines and atherosclerosis in ApoE-/- mice. Biomed Res Int. 2014;2014:548783.

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Molecular Weight (MW)684.81
Molecular Formula2C15H25NO3.C4H6O6
CAS No.56392-17-7
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 100 mg/mL (146.0 mM)r
Water: 100 mg/mL (146.0 mM)r
Ethanol: 31 mg/mL (45.2 mM)
Solubility In VivoChemical Name: (R)-1-(isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol hemi((2R)-2,3-dihydroxysuccinate) InChi Key: YGULWPYYGQCFMP-RBXXDJRDSA-N InChi Code: InChI=1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t2*14-;1-,2?/m111/s1 SMILES Code: O[C@H](CNC(C)C)COC1=CC=C(CCOC)C=C1.O[C@H](CNC(C)C)COC2=CC=C(CCOC)C=C2.O=C(O)[C@H](O)C(O)C(O)=O
SynonymsCGP 2175E; Lanoc; Lopressor; CGP2175E; CGP-2175E; Metomerck; Metop; Selopral; Ritmolol; Metoprolol Tartrate
ProtocolIn VivoMetoprolol (2.5 mg/kg/h; infusion; 11 weeks) reduces proinflammatory cytokines and atherosclerosis in ApoE−/− Mice
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.4603 mL7.3013 mL14.6026 mL29.2052 mL
5mM0.2921 mL1.4603 mL2.9205 mL5.8410 mL
10mM0.1460 mL0.7301 mL1.4603 mL2.9205 mL
20mM0.0730 mL0.3651 mL0.7301 mL1.4603 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.