ME-401 (P110δ-IN-1 )
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1550 | Check With Us |
| 500mg | $2250 | Check With Us |
| 1g | $3375 | Check With Us |
: Cat #: V25217 CAS #: 1595129-71-7 Purity ≥ 99%
Description: PWT143, formerly known as ME-401, is an orally bioavailable inhibitor of the delta isoform of phosphatidylinositide 3-kinase (PI3K), with potential antineoplastic activity.
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| Molecular Weight (MW) | 604.77 |
|---|---|
| Molecular Formula | C31H40N8O3S |
| CAS No. | 1595129-71-7 |
| SMILES Code | CN(CC1)CCC1C2=C(CC(C)(C)NC3=NC(N4CCOCC4)=NC(N5C(S(C)(=O)=O)=NC6=C5C=CC=C6)=N3)C=CC=C2 |
| Synonyms | ME-401; ME401; ME 401; Zandelisib; PWT143; PWT-143; PWT 143; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.6535 mL | 8.2676 mL | 16.5352 mL | 33.0704 mL |
| 5mM | 0.3307 mL | 1.6535 mL | 3.3070 mL | 6.6141 mL |
| 10mM | 0.1654 mL | 0.8268 mL | 1.6535 mL | 3.3070 mL |
| 20mM | 0.0827 mL | 0.4134 mL | 0.8268 mL | 1.6535 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.