MC-Gly-Gly-Phe

This product is for research use only, not for human use. We do not sell to patients.

MC-Gly-Gly-Phe
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1200Check With Us
500mg$1800Check With Us
1g$2700Check With Us

Cat #: V2286 CAS #: 1599440-15-9 Purity ≥ 99%

Description: MC-Gly-Gly-Phe is a novel linker commonly used in the synthesis of antibody-drug conjugates (ADC) in which it connects the antibody with the drug-load.

References: [1]. Antibody-drug conjugate. WO2014057687A1.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)472.49
Molecular FormulaC23H28N4O7
CAS No.1599440-15-9
SMILES CodeO=C(O)[C@H](CC1=CC=CC=C1)NC(CNC(CNC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O
SynonymsMC-Gly-Gly-Phe;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1164 mL10.5822 mL21.1645 mL42.3289 mL
5mM0.4233 mL2.1164 mL4.2329 mL8.4658 mL
10mM0.2116 mL1.0582 mL2.1164 mL4.2329 mL
20mM0.1058 mL0.5291 mL1.0582 mL2.1164 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.