Lovastatin | CAS 75330-75-5

Lovastatin

This product is for research use only, not for human use. We do not sell to patients.

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Size	Price	Stock
10g	$450	Check With Us
25g	$850	Check With Us
50g	$1275	Check With Us

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Cat #: V0926 CAS #: 75330-75-5 Purity ≥ 98%

Description: Lovastatin (Mevinolin; Mevacor; MK-803; Altoprev; Monacolin K; MK803), belonging to the statin class of hypolipidemic agent/lipid-lowering drugs, is a potent and cell-permeable inhibitor of HMG-CoA reductase with potential anti-hyperlipidemic effects.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	404.54
Molecular Formula	C24H36O5
CAS No.	75330-75-5
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 8 mg/mL (19.8 mM)r
	Water: <1 mg/mLr
	Ethanol: 6 mg/mL (14.8 mM)
Solubility In Vivo	30% PEG400+0.5% Tween80+5% propylene glycol: 30 mg/mL
SMILES Code	CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C
Synonyms	MK 803; MK803; Lovastatin; Mevinolin; Mevacor; MK-803; Altoprev; Monacolin K;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.4719 mL	12.3597 mL	24.7194 mL	49.4389 mL
5mM	0.4944 mL	2.4719 mL	4.9439 mL	9.8878 mL
10mM	0.2472 mL	1.2360 mL	2.4719 mL	4.9439 mL
20mM	0.1236 mL	0.6180 mL	1.2360 mL	2.4719 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.