lofexidine HCl
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
1g | $400 | Check With Us |
2g | $650 | Check With Us |
5g | $990 | Check With Us |
Cat #: V3893 CAS #: 21498-08-8 Purity ≥ 98%
Description: Lofexidine HCl (Lucemyra) is the hydrochloride salt of lofexidine which is an analog of Clonidine and an α2A adrenergic receptor agonist.
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Molecular Weight (MW) | 295.59 |
---|---|
Molecular Formula | C11H13Cl3N2O |
CAS No. | 21498-08-8 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: 10 mMr |
Water: N/Ar | |
Ethanol: N/A | |
SMILES Code | CC(C1=NCCN1)OC2=C(C=CC=C2Cl)Cl.Cl |
Synonyms | Lofexidine Hydrochloride; Lofetensin; Brand name Lucemyra; Lofexidine HCl; Loxacor;Lofexidine mono-hydrochloride; lofexidine (+-)-isomer |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 3.3831 mL | 16.9153 mL | 33.8306 mL | 67.6613 mL |
5mM | 0.6766 mL | 3.3831 mL | 6.7661 mL | 13.5323 mL |
10mM | 0.3383 mL | 1.6915 mL | 3.3831 mL | 6.7661 mL |
20mM | 0.1692 mL | 0.8458 mL | 1.6915 mL | 3.3831 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
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Volume(start)
V1
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Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.