L-Sepiapterin
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $3250 | Check With Us |
| 200mg | $4875 | Check With Us |
| 500mg | $8225 | Check With Us |
: Cat #: V40817 CAS #: 17094-01-8 Purity ≥ 99%
Description: L-Sepiapterin is a novel and potent precursor of tetrahydrobiopterin (BH4).
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 237.22 |
|---|---|
| Molecular Formula | C9H11N5O3 |
| CAS No. | 17094-01-8 |
| SMILES Code | O=C1N=C(N)NC2=C1N=C(C([C@@H](O)C)=O)CN2 |
| Synonyms | PTC 923; PTC-923; PTC923; Sepiapterin; Sepiapterine; L-Sepiapterin; CNSA 001; CNSA-001; CNSA001; |
| Protocol | In Vitro | L-Sepiapterin inhibits VEGF-A-induced cell proliferation and migration through NO-independent mechanism. L-Sepiapterin (1-50 μM; 20 minutes) significantly inhibits the phosphorylation of VEGF-A-induced (50 ng/ml) p70S6K. L-Sepiapterin (Sepiapterin) (0.1-10 μM; 24 hpurs) Iinduces cell proliferation in a dose-dependent manner. |
|---|---|---|
| In Vivo | Sepiapterin (10 mg/kg; p.o. (powder chow); daily for or 8 weeks) significantly improves the relaxation to Ach in small mesenteric arteries (SMA) from db/db mice. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.2155 mL | 21.0775 mL | 42.1550 mL | 84.3099 mL |
| 5mM | 0.8431 mL | 4.2155 mL | 8.4310 mL | 16.8620 mL |
| 10mM | 0.4215 mL | 2.1077 mL | 4.2155 mL | 8.4310 mL |
| 20mM | 0.2108 mL | 1.0539 mL | 2.1077 mL | 4.2155 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.