JTT 551 | CAS 776309-04-7

JTT 551

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
1mg	$230	To Be Confirmed
5mg	$560	To Be Confirmed
10mg	$880	To Be Confirmed

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Cat #: V29345 CAS #: 776309-04-7 Purity ≥ 99%

Description: JTT 551 is a selective protein tyrosine phosphatase 1B (PTP1B) inhibitor (antagonist) with Ki of 0.22 μM. It also has an effect on T cell protein tyrosine phosphatase (TCPTP) with Ki of 9.3 μM. It is available Research on type 2 diabetes.

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Molecular Weight (MW)	605.853526353836
Molecular Formula	C34H43N3O3S2
CAS No.	776309-04-7
Storage	Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture and light.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.6506 mL	8.2528 mL	16.5056 mL	33.0113 mL
5mM	0.3301 mL	1.6506 mL	3.3011 mL	6.6023 mL
10mM	0.1651 mL	0.8253 mL	1.6506 mL	3.3011 mL
20mM	0.0825 mL	0.4126 mL	0.8253 mL	1.6506 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.