JNJ303

This product is for research use only, not for human use. We do not sell to patients.

JNJ303
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1750Check With Us
500mg$2850Check With Us
1g$4275Check With Us

Cat #: V22954 CAS #: 878489-28-2 Purity ≥ 99%

Description: JNJ303 is a potent and specific inhibitor of heteromeric Kv7.1/KCNE1 channel complexes in a concentration- and time-dependent manner.

References: Julie Albrecht, et al. The effect of the KV7/KCNE 1 inhibitor JNJ 303 on heart slices and the L-type calcium channel of cardiac cells.

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Product Promise

Promise
Molecular Weight (MW)440.98
Molecular FormulaC21H29ClN2O4S
CAS No.878489-28-2
SynonymsJNJ303; JNJ-303; JNJ 303; AC-1; AC 1; AC1
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.2677 mL11.3384 mL22.6768 mL45.3535 mL
5mM0.4535 mL2.2677 mL4.5354 mL9.0707 mL
10mM0.2268 mL1.1338 mL2.2677 mL4.5354 mL
20mM0.1134 mL0.5669 mL1.1338 mL2.2677 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.