Isoscopoletin

This product is for research use only, not for human use. We do not sell to patients.

Isoscopoletin
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$803-6 Days
10mg$1203-6 Days
25mg$1903-6 Days
50mg$2903-6 Days
100mg$4403-6 Days

Cat #: V29343 CAS #: 776-86-3 Purity ≥ 99%

Description: Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active constituent in Artemisia argyi leaves.With IC50s of 4.0 μM and 1.6 μM for human CCRF-CEM leukaemia cells and multidrug-resistant subline CEM/ADR5000, respectively, isoscopoletin exhibits significant inhibition against cell proliferation[1]. There is inhibitory activity of isoscopoletin (6-hydroxy-7-methoxycoumarin) against HBV replication .

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Molecular Weight (MW)192.17
Molecular FormulaC10H8O4
CAS No.776-86-3
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Note: This product requires protection from light (avoid light exposure) during transportation and storage.

SynonymsIsoscopoletin; Esculetin 7-methyl ether; 7-methoxy-6-Hydroxycoumarin; 7-Methoxyesculetin; 7 Methoxyesculetin; 7Methoxyesculetin;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM5.2037 mL26.0186 mL52.0373 mL104.0745 mL
5mM1.0407 mL5.2037 mL10.4075 mL20.8149 mL
10mM0.5204 mL2.6019 mL5.2037 mL10.4075 mL
20mM0.2602 mL1.3009 mL2.6019 mL5.2037 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.