Irsogladine

This product is for research use only, not for human use. We do not sell to patients.

Irsogladine
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5g$650Check With Us
10g$950Check With Us
20g$1425Check With Us

Cat #: V0796 CAS #: 57381-26-7 Purity ≥ 98%

Description: Irsogladine (MN1695; MN 1695; Gaslon; MN-1695; Dicloguamine), a mucosal protective drug, is a novel and potent PDE4 inhibitor and muscarinic acetylcholine receptor binder with anti-ulceric activity.

References: Ren, C.J., et al., Irsogladine maleate inhibits angiogenesis in wild-type and plasminogen activator-deficient mice. J Surg Res, 1998. 77(2): p. 126-31.

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Product Promise

Promise
Molecular Weight (MW)256.09
Molecular FormulaC9H7Cl2N5
CAS No.57381-26-7
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 2 mg/mL (7.8 mM)r
Water:<1 mg/mLr
Ethanol: <1 mg/mL
SMILES CodeNc1nc(N)nc(n1)c2cc(Cl)ccc2Cl
SynonymsMN1695; MN 1695; Gaslon; MN-1695; Irsogladine maleate;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.9049 mL19.5244 mL39.0488 mL78.0975 mL
5mM0.7810 mL3.9049 mL7.8098 mL15.6195 mL
10mM0.3905 mL1.9524 mL3.9049 mL7.8098 mL
20mM0.1952 mL0.9762 mL1.9524 mL3.9049 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.