INCB024360 analogue

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
500mg	$580	Check With Us
1g	$850	Check With Us
5g	$2150	Check With Us

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Cat #: V0940 CAS #: 914471-09-3 Purity ≥ 98%

Description: INCB024360 analog (Epacadostat analog; INCB-024360 analog; IDO-IN-2), a hydroxyamidine-based compound, is an orally bioavailable and competitive inhibitor of IDO1 (indoleamine-(2,3)-dioxygenase) with potential immunomodulating and anticancer activities.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	271.64
Molecular Formula	C9H7ClFN5O2
CAS No.	914471-09-3
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 54 mg/mL (198.8 mM)r
	Water: <1 mg/mLr
	Ethanol: 54 mg/mL (198.8 mM)
Solubility In Vivo	2% DMSO+corn oil: 5mg/mL
SMILES Code	O/N=C(C1=NON=C1N)/NC2=CC=C(F)C(Cl)=C2
Synonyms	IDO-IN-2;INCB024360 analog; INCB24360 analog; Epacadostat analog

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.6813 mL	18.4067 mL	36.8134 mL	73.6269 mL
5mM	0.7363 mL	3.6813 mL	7.3627 mL	14.7254 mL
10mM	0.3681 mL	1.8407 mL	3.6813 mL	7.3627 mL
20mM	0.1841 mL	0.9203 mL	1.8407 mL	3.6813 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.