INCB024360 analog (Epacadostat analog; INCB-024360 analog; IDO-IN-2), a hydroxyamidine-based compound, is an orally bioavailable and competitive inhibitor of IDO1 (indoleamine-(2,3)-dioxygenase) with potential immunomodulating and anticancer activities.

IDO-IN-1 is a potent and selective indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50 of 59 nM.

IDO inhibitor 1 (IDO-IN-2) is a novel and potent small molecule inhibitor of the IDO enzyme (indoleamine-(2,3)-dioxygenase) with an IC50 of 3 nM in cell free assays, and IC50 values of 0.068 μM in HeLa cell and 0.16 μM in HEK293 cell.

Epacadostat (formerly INCB024360; IDO-IN-1; INCB-024360; INCB-24360; INCB24360) is an orally bioavailable, potent and selective IDO1 (indoleamine-(2,3)-dioxygenase) inhibitor with potential immunomodulating and antitumor activity.

NLG919 analog (RG6078 analog; GDC-0919 analog; GDC0919 analog; IDO-IN-7; NLG-919 analog) is a novel, potent and orally bioavailable inhibitor of IDO (indoleamine-(2,3)-dioxygenase) pathway with potential immunomodulating and antitumor activity.

8-Nitrotryptanthrin is a potent selective inhibitor of the human indoleamine 2,3-dioxygenase 2 (hIDO2) which dramatically reduces IDO2 activity with Ki value of 0.97 μM.

PF-06840003 (also known as PF06840003; EOS200271) is a highly potent and selective, orally bioavailable IDO-1 inhibitor (IC50 of 0.15 μM) with anticancer activity.

LM10 is a novel, potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) with IC50 values of 0.62 and 2 μM for human and mouse TDO, respectively. LM10 exhibits selectivity for TDO ver IDO, MAO-A, MAO-B, and a panel of receptors and transporters.

Navoximod (formerly known as IDO-IN-7; NLG-1488; NLG919) is a potent inhibitor of the IDO (indoleamine-(2,3)-dioxygenase) pathway (Ki/EC50 = 7 nM/75 nM) with potential immunomodulating and antineoplastic activities.

Linrodostat (formerly known as BMS-986205, ONO-7701 and F001287) is a novel, potent, orally bioactive and selective inhibitor of IDO (indoleamine 2,3-dioxygenase 1) with potential anticancer activities.