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IDO-IN-13 (GS4361)

This product is for research use only, not for human use. We do not sell to patients.

IDO-IN-13 (GS4361)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1750Check With Us
500mg$2550Check With Us
1g$3825Check With Us
email: [email protected]        [email protected]

Cat #: V37567 CAS #: 2291164-02-6 Purity ≥ 99%

Description: IDO-IN-13 (GS-4361), extracted from patent WO2019040102A1, example 43, is a novel and potent indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with EC50 of 17 nM.

References: Mark J. BARTLETT, et al. Therapeutic heterocyclic compounds. WO2019040102A1.

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Molecular Weight (MW)458.43
Molecular FormulaC26H17F3N4O
CAS No.2291164-02-6
SMILES CodeO=C(C1=CC(C2=CC=CN3C2=CN=C3C4=CC=CC(F)=C4F)=CN=C1C)NC5=CC=C(F)C=C5
SynonymsGS-4361; GS 4361; GS4361
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1814 mL10.9068 mL21.8136 mL43.6272 mL
5mM0.4363 mL2.1814 mL4.3627 mL8.7254 mL
10mM0.2181 mL1.0907 mL2.1814 mL4.3627 mL
20mM0.1091 mL0.5453 mL1.0907 mL2.1814 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
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C2
 
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.