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Ibandronate sodium monohydrate

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Ibandronate sodium monohydrate
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1g$400To Be Confirmed.
2g$650To Be Confirmed
5g$1095To Be Confirmed

Cat #: V12246 CAS #: 138926-19-9 Purity ≥ 99%

Description: Ibandronate sodium monohydrate (BM210955; RPR102289A) is a bisphosphonate drug used for the treatment of osteoporosis, acting by increasing bone mineral density, preventing resorption, and decreasing osteoclast activity.

References: Morgan, C., S. Jeremiah, and J. Wagstaff, Metronomic administration of ibandronate and its anti-angiogenic effects in vitro. Microvasc Res, 2009. 78(3): p. 453-8.

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Molecular Weight (MW)359.23
Molecular FormulaC9H24NNaO8P2
CAS No.138926-19-9
SMILES CodeCCCCCN(CCC(P([O-])(O)=O)(P(O)(O)=O)O)C.[H]O[H].[Na+]
SynonymsBoniva; Ibandronate sodium; Ibandronate sodium monohydrate; Sodium trihydrogen (1-hydroxy-3-(methylpentylamino)propylidene)diphosphonate, monohydrate
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.7837 mL13.9187 mL27.8373 mL55.6746 mL
5mM0.5567 mL2.7837 mL5.5675 mL11.1349 mL
10mM0.2784 mL1.3919 mL2.7837 mL5.5675 mL
20mM0.1392 mL0.6959 mL1.3919 mL2.7837 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.