MitoEbselen-2 (MitoPeroxidase-2), an Ebselen derivative, is a novel and potent radiation mitigator.
Grape Seed Extract is a natural product isolated from whole grape seeds that have a great concentration of vitamin E, flavonoids, linoleic acid, and OPCs.
Dp44mT is a novel and potent iron chelator with DNA-damaging activity mediated by top2a inhibition and with selective antitumor activity.
NSC 144303 (also known as Ubiquitin Isopeptidase Inhibitor I, G5) is a novel and potent apoptosome-independent caspase and apoptosis activator with IC50 values of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively.
Carubicin (Karminomitsin; Carminomicin I; karminomycin; Demethyldaunomycin), a potent anticancer agent and DNA intercalator, is a natural anthracycline antineoplastic antibiotic isolated from the bacterium Actinomadura carminata.
3′-Hydroxypterostilbene is a novel and potent pterostilbene analogue
Meisoindigo is a novel and potent apoptosis inducer.
Darinaparsin (ZIO-101, SP-02) is a novel and potent mitochondrial-targeted small molecule and an organic arsenic that is being developed for the treatment of various hematologic and solid cancers.
Lenalidomide hemihydrate (Revlimid, CC-5013) is a derivative of thalidomide approved in the United States in 2005 for the treatment for myeloma and blood disorders called myelodysplastic syndromes.
Angelicin (Isopsoralen) is a naturally occurring furocoumarin structurally related to psorally bioavailableens and is reported to have anti-cancer, antiviral, anti-inflammatory activity.